Hematology Practice Questions (ASCP MLS and MLT)
20–25% of the MLT exam · 17–22% of the MLS exam, in ASCP’s content guidelines
100 questions across all seven content areas in 2 hours 30 minutes, with a score for Hematology so you know where you stand.
Free Hematology drillTeardrop cells (dacryocytes) with a leukoerythroblastic picture suggest which condition?
Hematology on the ASCP exams
Hematology is 20–25% of the MLT exam and 17–22% of the MLS exam, and it includes hemostasis. Questions ask you to recognize disorders from counts, indices and smear findings, to troubleshoot analyzer results, and to interpret coagulation tests.
- Share of the exam
- MLT 20–25% (22 of 100 on our MLT mock) · MLS 17–22% (20 of 100 on our MLS mock)
- Our drill
- 10 questions from 77 hematology questions, untimed, an explanation after every answer; one free attempt, unlimited with a pass
What Hematology questions test
- Physiology: production, function and destruction of red cells, white cells and platelets
- Red cell disorders: microcytic, normocytic and macrocytic anemias, hemolytic anemias, hemoglobinopathies and thalassemias
- White cell disorders: reactive changes, acute leukemias, myeloproliferative and lymphoid neoplasms, plasma cell disorders and their genetic markers
- Laboratory testing: manual and automated counts, spurious results, indices and corrected counts, morphology, special stains and flow cytometry
- Hemostasis: coagulation pathways, PT/INR, APTT, mixing studies, D-dimer, factor deficiencies, DIC, thrombophilia and anticoagulant monitoring
Sit the full exam under the real clock
100 questions across all seven content areas in 2 hours 30 minutes, with a score for Hematology so you know where you stand.
Free Hematology drillHow to study it
- Practice the index calculations (MCV, MCH, MCHC) and corrected WBC counts until they are automatic.
- Learn the analyzer errors from cold agglutinins, lipemia, platelet clumps and nucleated red cells.
- For coagulation, sort each factor into the PT, the APTT or both before memorizing disorders.
Common questions
Is coagulation part of hematology on the ASCP exam?
Yes. ASCP’s hematology area covers hemostasis: physiology, disease states and laboratory determinations such as PT/INR, APTT, fibrinogen, D-dimer, mixing studies and anti-Xa.
How many hematology questions are on the mock exams?
Our MLT mock has 22 hematology questions and our MLS mock 20, inside ASCP’s ranges of 20–25% and 17–22%.
100 questions across all seven content areas in 2 hours 30 minutes, with a score for Hematology so you know where you stand.
Free Hematology drillThe other content areas
Sources
- ASCP BOC: MLT and MLS Examination Content Guidelines (revised June 9, 2026)
- ASCP BOC: About the Examination (format, CAT, scoring, field test questions, calculator)
- ASCP BOC: Medical Laboratory Technician, MLT(ASCP): eligibility routes and $235 fee
- ASCP BOC: Medical Laboratory Scientist, MLS(ASCP): eligibility routes and $260 fee
- ASCP BOC: Examination Results
- ASCP BOC: After the Examination (re-applying, five attempts per route, 30-day wait)
- ASCP BOC: Schedule or Reschedule Your Examination (Pearson testing centers)
- ASCP BOC: MLS and MLT Credential Maintenance Program requirements (36 points, three years)
Original practice questions for exam preparation, written to the ASCP BOC MLT and MLS Examination Content Guidelines (revised June 9, 2026), not ASCP exam questions. Independent practice, not affiliated with or endorsed by the American Society for Clinical Pathology (ASCP), the ASCP Board of Certification or Pearson VUE.