FNP Musculoskeletal and Neurology Practice Questions
Original FNP board practice questions on musculoskeletal and neurology, for the AANPCB and ANCC exams
150 questions in 3 hours, drawn to AANPCB’s domain and age counts, with a score for Musculoskeletal and Neuro and an explanation for every answer.
Free Musculoskeletal and Neuro drillA 79-year-old has mild-to-moderate Alzheimer disease. Which medication class is first-line for symptoms?
Musculoskeletal and Neurology on the FNP board exams
These questions mix physical exam maneuvers with urgent decisions: a red flag in back pain, a thunderclap headache, a sudden facial droop. Many involve older adults, the largest age group on the AANPCB blueprint.
- On the exams
- Not counted separately by either owner; tested across AANPCB’s four practice domains and ANCC’s five content domains
- Our drill
- 10 questions from 56 musculoskeletal and neuro questions, untimed, an explanation after every answer; one free attempt, unlimited with a pass

What musculoskeletal and neurology questions test
- Low back pain without imaging, red flags, sciatica and spinal stenosis
- Knee, shoulder, wrist and ankle exams (Lachman, McMurray, Finkelstein, Ottawa rules) and common injuries
- Osteoarthritis, rheumatoid arthritis, polymyalgia rheumatica and septic arthritis
- Migraine and cluster headache, subarachnoid hemorrhage, stroke and TIA, Bell palsy, seizures and concussion
- Parkinson disease, essential tremor, dementia types, delirium, falls (STEADI) and safe opioid prescribing
Sit the full exam under the real clock
150 questions in 3 hours, drawn to AANPCB’s domain and age counts, with a score for Musculoskeletal and Neuro and an explanation for every answer.
Free Musculoskeletal and Neuro drillHow to study it
- Pair each special test with the structure it tests.
- Learn the difference between delirium (acute, fluctuating, inattentive) and dementia.
- Take the musculoskeletal and neuro drill, then the older adults drill.
Common questions
How many musculoskeletal and neuro questions are on the FNP exam?
Neither exam publishes a question count per body system. ANCC lists body systems, drug classes and age groups as secondary classifications of its five domains; AANPCB weights its exam by practice domain and patient age.
Are falls and dementia tested on the FNP exam?
Older adults are the largest AANPCB age group (40 of 135 scored items), and ANCC lists older adult and frail elderly among its age groups and functional and cognitive assessment in its Assessment domain.
150 questions in 3 hours, drawn to AANPCB’s domain and age counts, with a score for Musculoskeletal and Neuro and an explanation for every answer.
Free Musculoskeletal and Neuro drillMore FNP practice
- AANPCB FNP exam
- ANCC FNP-BC exam
- Cardiovascular and Hematology
- Respiratory
- Endocrine and Metabolic
- Gastrointestinal
- Renal, Urinary and Men’s Health
- Women’s Health and Prenatal Care
- Pediatrics and Adolescents
- HEENT and Dermatology
- Mental Health and Substance Use
- Professional Practice, Ethics and Policy
- AANPCB practice exam (150 questions, 3 hours)
- ANCC practice exam (175 questions, 3.5 hours)
Sources
- AANPCB (NPCB): Family Nurse Practitioner Candidate Handbook (updated 06/2026): format, timing, blueprint, scoring, retakes
- AANPCB: Family NP exam page (test blueprint) and fees
- AANPCB: Practice exams (50 questions, 60 minutes, $50)
- AANPCB: 2025 certification statistics
- ANCC: Family Nurse Practitioner certification (FNP-BC): fees, format, renewal
- ANCC: FNP-BC Test Content Outline, effective October 30, 2026
- ANCC Certification Handbook (October 2026): scoring (350 of 500) and retesting
- ANCC: FNP reference list, effective October 30, 2026
- ANCC: 2025 certification data (first-time pass rates)
Original practice questions for exam preparation, written to the AANPCB FNP blueprint and the ANCC FNP-BC Test Content Outline effective October 30, 2026, not AANPCB or ANCC exam questions. Independent practice, not affiliated with or endorsed by AANPCB (NPCB), AANP, ANCC or Prometric. NP-C is a certification mark of NPCB; FNP-BC is an ANCC credential.