FNP Musculoskeletal and Neurology Practice Questions

Original FNP board practice questions on musculoskeletal and neurology, for the AANPCB and ANCC exams

150 questions in 3 hours, drawn to AANPCB’s domain and age counts, with a score for Musculoskeletal and Neuro and an explanation for every answer.

Free Musculoskeletal and Neuro drill
Free sample · Question 1 of 3Musculoskeletal and Neuro

A 79-year-old has mild-to-moderate Alzheimer disease. Which medication class is first-line for symptoms?

Choose the best answer

Musculoskeletal and Neurology on the FNP board exams

These questions mix physical exam maneuvers with urgent decisions: a red flag in back pain, a thunderclap headache, a sudden facial droop. Many involve older adults, the largest age group on the AANPCB blueprint.

On the exams
Not counted separately by either owner; tested across AANPCB’s four practice domains and ANCC’s five content domains
Our drill
10 questions from 56 musculoskeletal and neuro questions, untimed, an explanation after every answer; one free attempt, unlimited with a pass
Line drawing of a spine and pelvis model on a stand beside a hinged knee brace and a wheeled walker

What musculoskeletal and neurology questions test

  • Low back pain without imaging, red flags, sciatica and spinal stenosis
  • Knee, shoulder, wrist and ankle exams (Lachman, McMurray, Finkelstein, Ottawa rules) and common injuries
  • Osteoarthritis, rheumatoid arthritis, polymyalgia rheumatica and septic arthritis
  • Migraine and cluster headache, subarachnoid hemorrhage, stroke and TIA, Bell palsy, seizures and concussion
  • Parkinson disease, essential tremor, dementia types, delirium, falls (STEADI) and safe opioid prescribing

Sit the full exam under the real clock

150 questions in 3 hours, drawn to AANPCB’s domain and age counts, with a score for Musculoskeletal and Neuro and an explanation for every answer.

Free Musculoskeletal and Neuro drill

How to study it

  • Pair each special test with the structure it tests.
  • Learn the difference between delirium (acute, fluctuating, inattentive) and dementia.
  • Take the musculoskeletal and neuro drill, then the older adults drill.

Common questions

How many musculoskeletal and neuro questions are on the FNP exam?

Neither exam publishes a question count per body system. ANCC lists body systems, drug classes and age groups as secondary classifications of its five domains; AANPCB weights its exam by practice domain and patient age.

Are falls and dementia tested on the FNP exam?

Older adults are the largest AANPCB age group (40 of 135 scored items), and ANCC lists older adult and frail elderly among its age groups and functional and cognitive assessment in its Assessment domain.

150 questions in 3 hours, drawn to AANPCB’s domain and age counts, with a score for Musculoskeletal and Neuro and an explanation for every answer.

Free Musculoskeletal and Neuro drill

More FNP practice

Sources

Original practice questions for exam preparation, written to the AANPCB FNP blueprint and the ANCC FNP-BC Test Content Outline effective October 30, 2026, not AANPCB or ANCC exam questions. Independent practice, not affiliated with or endorsed by AANPCB (NPCB), AANP, ANCC or Prometric. NP-C is a certification mark of NPCB; FNP-BC is an ANCC credential.