FNP Mental Health and Substance Use Practice Questions
Original FNP board practice questions on mental health and substance use, for the AANPCB and ANCC exams
150 questions in 3 hours, drawn to AANPCB’s domain and age counts, with a score for Mental Health and an explanation for every answer.
Free Mental Health drillWhich tool screens adolescents for substance use risk?
Mental Health and Substance Use on the FNP board exams
Primary care treats most depression and anxiety, so both exams test screening tools, first-line drugs and their risks, suicide assessment and substance use disorders.
- On the exams
- Not counted separately by either owner; tested across AANPCB’s four practice domains and ANCC’s five content domains
- Our drill
- 10 questions from 45 mental health questions, untimed, an explanation after every answer; one free attempt, unlimited with a pass
What mental health and substance use questions test
- Screening with the PHQ-2/PHQ-9, GAD-7, EPDS, GDS, AUDIT-C and CRAFFT
- SSRIs and SNRIs: choosing, the boxed warning, discontinuation and serotonin syndrome
- Bipolar disorder (screen before an antidepressant), lithium interactions, schizophrenia and antipsychotic monitoring
- Suicide risk assessment, lethal means counseling and the 988 crisis line
- Alcohol withdrawal and use disorder, opioid use disorder and buprenorphine, naloxone, benzodiazepine tapering and insomnia
Sit the full exam under the real clock
150 questions in 3 hours, drawn to AANPCB’s domain and age counts, with a score for Mental Health and an explanation for every answer.
Free Mental Health drillHow to study it
- Know which antidepressants to avoid in older adults (tricyclics, paroxetine) and why.
- Remember that the federal X-waiver for buprenorphine ended in 2023.
- Take the mental health drill until you score 80% or better.
Common questions
How many mental health questions are on the FNP exam?
Neither exam publishes a question count per body system. ANCC lists body systems, drug classes and age groups as secondary classifications of its five domains; AANPCB weights its exam by practice domain and patient age.
Is psychiatric content on the FNP exam?
Yes. ANCC lists the psychiatric system and psychiatric drugs among its secondary classifications, and AANPCB lists psychological assessment among its applied knowledge areas.
150 questions in 3 hours, drawn to AANPCB’s domain and age counts, with a score for Mental Health and an explanation for every answer.
Free Mental Health drillMore FNP practice
- AANPCB FNP exam
- ANCC FNP-BC exam
- Cardiovascular and Hematology
- Respiratory
- Endocrine and Metabolic
- Gastrointestinal
- Renal, Urinary and Men’s Health
- Women’s Health and Prenatal Care
- Pediatrics and Adolescents
- HEENT and Dermatology
- Musculoskeletal and Neurology
- Professional Practice, Ethics and Policy
- AANPCB practice exam (150 questions, 3 hours)
- ANCC practice exam (175 questions, 3.5 hours)
Sources
- AANPCB (NPCB): Family Nurse Practitioner Candidate Handbook (updated 06/2026): format, timing, blueprint, scoring, retakes
- AANPCB: Family NP exam page (test blueprint) and fees
- AANPCB: Practice exams (50 questions, 60 minutes, $50)
- AANPCB: 2025 certification statistics
- ANCC: Family Nurse Practitioner certification (FNP-BC): fees, format, renewal
- ANCC: FNP-BC Test Content Outline, effective October 30, 2026
- ANCC Certification Handbook (October 2026): scoring (350 of 500) and retesting
- ANCC: FNP reference list, effective October 30, 2026
- ANCC: 2025 certification data (first-time pass rates)
Original practice questions for exam preparation, written to the AANPCB FNP blueprint and the ANCC FNP-BC Test Content Outline effective October 30, 2026, not AANPCB or ANCC exam questions. Independent practice, not affiliated with or endorsed by AANPCB (NPCB), AANP, ANCC or Prometric. NP-C is a certification mark of NPCB; FNP-BC is an ANCC credential.