FNP Endocrine Practice Questions
Original FNP board practice questions on endocrine and metabolic, for the AANPCB and ANCC exams
150 questions in 3 hours, drawn to AANPCB’s domain and age counts, with a score for Endocrine and an explanation for every answer.
Free Endocrine drillA 29-year-old woman has palpitations, weight loss, heat intolerance and a diffusely enlarged, nontender thyroid with a bruit. She has proptosis. TSH is undetectable and free T4 is high. What is the most likely cause?
Endocrine and Metabolic on the FNP board exams
Diabetes and thyroid disease are among the most common chronic conditions in family practice. Expect questions on diagnostic cutoffs, choosing drugs by comorbidity, insulin starts, A1C goals by age and health, and drug adverse effects.
- On the exams
- Not counted separately by either owner; tested across AANPCB’s four practice domains and ANCC’s five content domains
- Our drill
- 10 questions from 48 endocrine questions, untimed, an explanation after every answer; one free attempt, unlimited with a pass
What endocrine and metabolic questions test
- Diagnosis of diabetes and prediabetes, screening ages, annual eye, foot and kidney checks
- Drug choice: metformin, GLP-1 receptor agonists and SGLT2 inhibitors for ASCVD, heart failure or CKD, and drugs to avoid in older adults
- Insulin starts and titration, hypoglycemia treatment, sick-day rules, DKA
- Hypothyroidism, hyperthyroidism and Graves disease, thyroid nodules, Cushing syndrome and adrenal insufficiency
- Obesity medicines, PCOS, hyperprolactinemia, hyperparathyroidism and gout
Sit the full exam under the real clock
150 questions in 3 hours, drawn to AANPCB’s domain and age counts, with a score for Endocrine and an explanation for every answer.
Free Endocrine drillHow to study it
- Know the diagnostic numbers cold: A1C 6.5%, fasting glucose 126 mg/dL, OGTT 200 mg/dL; prediabetes A1C 5.7–6.4%.
- Match each diabetes drug class to its key adverse effect and contraindication.
- Take the endocrine drill until you score 80% or better.
Common questions
How many endocrine questions are on the FNP exam?
Neither exam publishes a question count per body system. ANCC lists body systems, drug classes and age groups as secondary classifications of its five domains; AANPCB weights its exam by practice domain and patient age.
Which diabetes guideline do our questions use?
The ADA Standards of Care in Diabetes 2026, which is also on the ANCC FNP reference list.
150 questions in 3 hours, drawn to AANPCB’s domain and age counts, with a score for Endocrine and an explanation for every answer.
Free Endocrine drillMore FNP practice
- AANPCB FNP exam
- ANCC FNP-BC exam
- Cardiovascular and Hematology
- Respiratory
- Gastrointestinal
- Renal, Urinary and Men’s Health
- Women’s Health and Prenatal Care
- Pediatrics and Adolescents
- HEENT and Dermatology
- Musculoskeletal and Neurology
- Mental Health and Substance Use
- Professional Practice, Ethics and Policy
- AANPCB practice exam (150 questions, 3 hours)
- ANCC practice exam (175 questions, 3.5 hours)
Sources
- AANPCB (NPCB): Family Nurse Practitioner Candidate Handbook (updated 06/2026): format, timing, blueprint, scoring, retakes
- AANPCB: Family NP exam page (test blueprint) and fees
- AANPCB: Practice exams (50 questions, 60 minutes, $50)
- AANPCB: 2025 certification statistics
- ANCC: Family Nurse Practitioner certification (FNP-BC): fees, format, renewal
- ANCC: FNP-BC Test Content Outline, effective October 30, 2026
- ANCC Certification Handbook (October 2026): scoring (350 of 500) and retesting
- ANCC: FNP reference list, effective October 30, 2026
- ANCC: 2025 certification data (first-time pass rates)
Original practice questions for exam preparation, written to the AANPCB FNP blueprint and the ANCC FNP-BC Test Content Outline effective October 30, 2026, not AANPCB or ANCC exam questions. Independent practice, not affiliated with or endorsed by AANPCB (NPCB), AANP, ANCC or Prometric. NP-C is a certification mark of NPCB; FNP-BC is an ANCC credential.