USMLE Step 2 CK Nervous System Practice Questions

5–10% of Step 2 CK · 30 practice questions with a note on every option

316 questions in 16 timed 30-minute blocks, with your score in nervous system and every other content area.

Free nervous system drill
Free sample · Question 1 of 3Nervous System

A 66-year-old man is brought to the emergency department 90 minutes after his wife found him with sudden weakness of his right arm and leg and difficulty speaking; he had been normal 15 minutes earlier. He takes amlodipine for hypertension. Blood pressure is 172/96 mm Hg, pulse is 84/min and regular, and fingerstick glucose is 132 mg/dL. He has expressive aphasia and right hemiparesis; the NIH Stroke Scale score is 10. Noncontrast CT of the head shows no hemorrhage or established infarct, and CT angiography shows no large-vessel occlusion. He takes no anticoagulants and has had no recent surgery or bleeding. Platelet count and INR are normal. Which of the following is the most appropriate next step in management?

Nervous System & Special Senses on Step 2 CK

Nervous System & Special Senses is 5–10% of Step 2 CK. Time-critical decisions dominate: acute stroke, status epilepticus, head injury and spinal cord compression, with eye and ENT emergencies in the same category.

Share of Step 2 CK
5–10% of the exam, per the USMLE content outline
On our mock exam
24 of 316 questions, with your score for this system in the result
Our drill
10 questions from 30 nervous system questions, untimed, a note on every option; one free attempt, unlimited with a pass
Line drawing of a brain model, an ophthalmoscope, an otoscope, a tuning fork and a reflex hammer

What Step 2 CK nervous system questions test

  • Acute stroke: imaging first, thrombolysis and thrombectomy windows, and secondary prevention
  • Seizures and status epilepticus
  • Headache red flags: subarachnoid hemorrhage, meningitis and giant cell arteritis
  • Head injury, raised intracranial pressure and spinal cord emergencies
  • Neuromuscular disease: myasthenia gravis, Guillain-Barré syndrome and ALS
  • Eye and ENT emergencies: acute angle-closure glaucoma, retinal artery occlusion and epistaxis

Sit all 316 questions in timed blocks

316 questions in 16 timed 30-minute blocks, with your score in nervous system and every other content area.

Free nervous system drill

How to study it

  • Learn the order of steps in acute stroke and status epilepticus.
  • Know which headaches need imaging or a lumbar puncture today.
  • Separate upper from lower motor neuron findings before you name a disease.

Common questions

Are eye problems tested on Step 2 CK?

Yes. The eye and ear sit in Nervous System & Special Senses (5–10% of Step 2 CK). Questions focus on emergencies that threaten vision.

How many neurology questions are on our mock?

24 of 316, inside the content outline’s 5–10% range.

316 questions in 16 timed 30-minute blocks, with your score in nervous system and every other content area.

Free nervous system drill

The other Step 2 CK systems

Sources

Original practice questions written to the USMLE content outlines and current standard references. USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and NBME. Independent practice, not affiliated with or endorsed by the FSMB, NBME or Intealth (ECFMG). Follow current guidelines in clinical practice.