USMLE Step 2 CK Cardiovascular Practice Questions
6–12% of Step 2 CK · 34 practice questions with a note on every option
316 questions in 16 timed 30-minute blocks, with your score in cardiovascular and every other content area.
Free cardiovascular drillA 78-year-old woman with atrial fibrillation who stopped taking apixaban 2 weeks ago comes to the emergency department because of sudden severe pain in her left leg for 3 hours. The left foot and calf are cold and pale. Femoral pulse is present on the left, but popliteal and pedal pulses are absent, and no Doppler signal is heard over the pedal arteries. Light-touch sensation is mildly decreased over the toes, and she can move her toes. Which of the following is the most appropriate next step in management?
Cardiovascular System on Step 2 CK
The Cardiovascular System is 6–12% of Step 2 CK. Questions follow a patient from the emergency department to clinic: chest pain, arrhythmias and shock first, then secondary prevention, blood pressure and lipids.
- Share of Step 2 CK
- 6–12% of the exam, per the USMLE content outline
- On our mock exam
- 28 of 316 questions, with your score for this system in the result
- Our drill
- 10 questions from 34 cardiovascular questions, untimed, a note on every option; one free attempt, unlimited with a pass
What Step 2 CK cardiovascular questions test
- Acute coronary syndromes, reperfusion and secondary prevention
- Heart failure with reduced and preserved ejection fraction
- Atrial fibrillation, other arrhythmias, syncope and resuscitation algorithms
- Hypertension and lipid management
- Valvular disease, endocarditis and pericardial disease
- Aortic dissection, aneurysm and peripheral artery disease
Sit all 316 questions in timed blocks
316 questions in 16 timed 30-minute blocks, with your score in cardiovascular and every other content area.
Free cardiovascular drillHow to study it
- Learn the first step for each emergency before the long-term drugs.
- Know the drug classes that lower mortality in heart failure with reduced ejection fraction.
- Learn the stable versus unstable branch point in each arrhythmia algorithm.
Common questions
Which guidelines do cardiology questions follow?
Current ACC/AHA guidelines, including the 2025 high blood pressure guideline and the 2025 acute coronary syndromes guideline, and the AHA guidelines for CPR and emergency cardiovascular care.
How many cardiovascular questions are on our Step 2 CK mock?
28 of 316, inside the content outline’s 6–12% range.
316 questions in 16 timed 30-minute blocks, with your score in cardiovascular and every other content area.
Free cardiovascular drillThe other Step 2 CK systems
Sources
- USMLE: Step 1 (blocks, items, testing day, break time)
- USMLE: Step 2 CK (blocks, items, testing day, break time)
- USMLE: Test delivery software updates for Step 2 CK and Step 1 (May 2026)
- USMLE: Step 1 content outline and specifications
- USMLE: Step 2 CK content outline and specifications
- USMLE: Examination results and scoring (minimum passing scores)
- USMLE Bulletin: Scoring and score reporting (about 60% correct to pass; result timing)
- USMLE Bulletin: Eligibility (attempt limits)
- USMLE: Apply for exams (2026 and 2027 fees, FSMB registration, region fees)
- USMLE: Performance data (pass rates)
- Intealth ECFMG: Fees overview (ECFMG Certification)
Original practice questions written to the USMLE content outlines and current standard references. USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and NBME. Independent practice, not affiliated with or endorsed by the FSMB, NBME or Intealth (ECFMG). Follow current guidelines in clinical practice.