USMLE Step 2 CK Musculoskeletal and Skin Practice Questions
6–12% of Step 2 CK · 34 practice questions with a note on every option
316 questions in 16 timed 30-minute blocks, with your score in musculoskeletal and skin and every other content area.
Free musculoskeletal and skin drillA 44-year-old woman has 4 months of pain and 90 minutes of morning stiffness in both hands. Examination shows swelling and tenderness of the second and third metacarpophalangeal joints and both wrists. Rheumatoid factor and anti-cyclic citrullinated peptide antibodies are positive, and erythrocyte sedimentation rate is 48 mm/h. Hand radiographs show periarticular osteopenia without erosions. Liver enzymes, creatinine, and hepatitis B and C serologies are normal. She uses an intrauterine device and does not plan pregnancy. Which of the following is the most appropriate initial disease-modifying therapy?
Musculoskeletal System/Skin & Subcutaneous Tissue on Step 2 CK
Musculoskeletal System/Skin & Subcutaneous Tissue is 6–12% of Step 2 CK. It covers orthopedic emergencies, rheumatology and dermatology, and many questions turn on choosing the right first test or the urgent step.
- Share of Step 2 CK
- 6–12% of the exam, per the USMLE content outline
- On our mock exam
- 28 of 316 questions, with your score for this system in the result
- Our drill
- 10 questions from 34 musculoskeletal and skin questions, untimed, a note on every option; one free attempt, unlimited with a pass
What Step 2 CK musculoskeletal and skin questions test
- Fractures, dislocations, compartment syndrome and open fractures
- Back pain, its red flags and spinal emergencies
- Septic arthritis, gout, rheumatoid arthritis and other inflammatory arthritis
- Pediatric orthopedics: slipped capital femoral epiphysis, developmental dysplasia of the hip, Legg-Calvé-Perthes disease
- Rashes, skin infections, drug eruptions and burns
- Skin cancer recognition and management
Sit all 316 questions in timed blocks
316 questions in 16 timed 30-minute blocks, with your score in musculoskeletal and skin and every other content area.
Free musculoskeletal and skin drillHow to study it
- For the swollen hot joint, think septic arthritis first and learn the next step.
- Learn which orthopedic findings need surgery today.
- Group rashes by appearance and distribution, then by cause.
Common questions
How much dermatology is on Step 2 CK?
Skin sits in this category, which the content outline puts at 6–12% of Step 2 CK together with musculoskeletal disease.
Are images used?
The real exam uses photographs. Our questions describe lesions in words, so learn the terms that point to each diagnosis.
316 questions in 16 timed 30-minute blocks, with your score in musculoskeletal and skin and every other content area.
Free musculoskeletal and skin drillThe other Step 2 CK systems
Sources
- USMLE: Step 1 (blocks, items, testing day, break time)
- USMLE: Step 2 CK (blocks, items, testing day, break time)
- USMLE: Test delivery software updates for Step 2 CK and Step 1 (May 2026)
- USMLE: Step 1 content outline and specifications
- USMLE: Step 2 CK content outline and specifications
- USMLE: Examination results and scoring (minimum passing scores)
- USMLE Bulletin: Scoring and score reporting (about 60% correct to pass; result timing)
- USMLE Bulletin: Eligibility (attempt limits)
- USMLE: Apply for exams (2026 and 2027 fees, FSMB registration, region fees)
- USMLE: Performance data (pass rates)
- Intealth ECFMG: Fees overview (ECFMG Certification)
Original practice questions written to the USMLE content outlines and current standard references. USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and NBME. Independent practice, not affiliated with or endorsed by the FSMB, NBME or Intealth (ECFMG). Follow current guidelines in clinical practice.