USMLE Step 2 CK Biostatistics and Epidemiology Practice Questions
3–5% of Step 2 CK · 15 practice questions with a note on every option
316 questions in 16 timed 30-minute blocks, with your score in biostatistics and epidemiology and every other content area.
Free biostatistics and epidemiology drillTwo to six hours after a church picnic, 60 of 120 attendees developed vomiting and abdominal cramps. Investigators collect food histories. Potato salad: 45 of 50 who ate it became ill, compared with 15 of 70 who did not. Chicken: 42 of 80 who ate it became ill, compared with 18 of 40 who did not. Lemonade: 46 of 90 who drank it became ill, compared with 14 of 30 who did not. Which of the following is the most likely source of the outbreak?
Biostatistics & Epidemiology/Population Health/Interpretation of Medical Literature on Step 2 CK
Biostatistics & Epidemiology/Population Health/Interpretation of Medical Literature is 3–5% of Step 2 CK. Beyond calculations, Step 2 CK asks you to read a study and judge what it shows.
- Share of Step 2 CK
- 3–5% of the exam, per the USMLE content outline
- On our mock exam
- 12 of 316 questions, with your score for this system in the result
- Our drill
- 10 questions from 15 biostatistics and epidemiology questions, untimed, a note on every option; one free attempt, unlimited with a pass
What Step 2 CK biostatistics and epidemiology questions test
- Sensitivity, specificity, predictive values and likelihood ratios
- Number needed to treat and to harm
- Study design, bias and confounding
- Reading an abstract and judging its conclusion
- Screening principles and lead-time and length-time bias
- Outbreak investigation
Sit all 316 questions in timed blocks
316 questions in 16 timed 30-minute blocks, with your score in biostatistics and epidemiology and every other content area.
Free biostatistics and epidemiology drillHow to study it
- Build the two-by-two table every time.
- Read the study design first; it limits what the results can show.
- Practice abstract questions by asking what the study cannot conclude.
Common questions
Are there abstract questions on Step 2 CK?
Interpretation of medical literature is part of this category. Expect a short study summary and questions on its design, results and limits.
How many questions on our mock?
12 of 316, inside the content outline’s 3–5% range.
316 questions in 16 timed 30-minute blocks, with your score in biostatistics and epidemiology and every other content area.
Free biostatistics and epidemiology drillThe other Step 2 CK systems
Sources
- USMLE: Step 1 (blocks, items, testing day, break time)
- USMLE: Step 2 CK (blocks, items, testing day, break time)
- USMLE: Test delivery software updates for Step 2 CK and Step 1 (May 2026)
- USMLE: Step 1 content outline and specifications
- USMLE: Step 2 CK content outline and specifications
- USMLE: Examination results and scoring (minimum passing scores)
- USMLE Bulletin: Scoring and score reporting (about 60% correct to pass; result timing)
- USMLE Bulletin: Eligibility (attempt limits)
- USMLE: Apply for exams (2026 and 2027 fees, FSMB registration, region fees)
- USMLE: Performance data (pass rates)
- Intealth ECFMG: Fees overview (ECFMG Certification)
Original practice questions written to the USMLE content outlines and current standard references. USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and NBME. Independent practice, not affiliated with or endorsed by the FSMB, NBME or Intealth (ECFMG). Follow current guidelines in clinical practice.