USMLE Step 2 CK Gastrointestinal Practice Questions
5–10% of Step 2 CK · 28 practice questions with a note on every option
316 questions in 16 timed 30-minute blocks, with your score in gastrointestinal and every other content area.
Free gastrointestinal drillAn 82-year-old man who lives in a nursing home and has Parkinson disease and chronic constipation is brought to the emergency department because of 2 days of progressive abdominal distension and no bowel movements. Temperature is 37.1°C (98.8°F), pulse is 98/min, and blood pressure is 128/76 mm Hg. The abdomen is markedly distended and tympanic with mild diffuse tenderness and no peritoneal signs. Lactate is normal. Abdominal radiograph shows a massively dilated, inverted U-shaped loop of sigmoid colon extending toward the right upper quadrant. Which of the following is the most appropriate next step in management?
Gastrointestinal System on Step 2 CK
The Gastrointestinal System is 5–10% of Step 2 CK. Many questions are surgical decisions: who needs imaging, who needs endoscopy and who needs the operating room.
- Share of Step 2 CK
- 5–10% of the exam, per the USMLE content outline
- On our mock exam
- 23 of 316 questions, with your score for this system in the result
- Our drill
- 10 questions from 28 gastrointestinal questions, untimed, a note on every option; one free attempt, unlimited with a pass

What Step 2 CK gastrointestinal questions test
- Upper and lower GI bleeding and resuscitation
- The acute abdomen: appendicitis, obstruction, perforation and mesenteric ischemia
- Pancreatitis, gallstone disease, cholecystitis and cholangitis
- Liver disease: hepatitis, cirrhosis and its complications
- Inflammatory bowel disease and celiac disease
- Colorectal cancer screening and pediatric GI conditions
Sit all 316 questions in timed blocks
316 questions in 16 timed 30-minute blocks, with your score in gastrointestinal and every other content area.
Free gastrointestinal drillHow to study it
- Learn the first imaging test for each abdominal presentation.
- Know when to scope, when to scan and when to operate.
- Learn colorectal screening by age and risk, from age 45 for average risk.
Common questions
Is surgery a big part of Step 2 CK?
Surgery is 5–15% of Step 2 CK as a discipline, and much of it appears in GI questions about the acute abdomen.
How many GI questions are on our mock?
23 of 316, inside the content outline’s 5–10% range.
316 questions in 16 timed 30-minute blocks, with your score in gastrointestinal and every other content area.
Free gastrointestinal drillThe other Step 2 CK systems
Sources
- USMLE: Step 1 (blocks, items, testing day, break time)
- USMLE: Step 2 CK (blocks, items, testing day, break time)
- USMLE: Test delivery software updates for Step 2 CK and Step 1 (May 2026)
- USMLE: Step 1 content outline and specifications
- USMLE: Step 2 CK content outline and specifications
- USMLE: Examination results and scoring (minimum passing scores)
- USMLE Bulletin: Scoring and score reporting (about 60% correct to pass; result timing)
- USMLE Bulletin: Eligibility (attempt limits)
- USMLE: Apply for exams (2026 and 2027 fees, FSMB registration, region fees)
- USMLE: Performance data (pass rates)
- Intealth ECFMG: Fees overview (ECFMG Certification)
Original practice questions written to the USMLE content outlines and current standard references. USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and NBME. Independent practice, not affiliated with or endorsed by the FSMB, NBME or Intealth (ECFMG). Follow current guidelines in clinical practice.