USMLE Step 2 CK Multisystem Processes Practice Questions
4–8% of Step 2 CK · 24 practice questions with a note on every option
316 questions in 16 timed 30-minute blocks, with your score in multisystem processes and every other content area.
Free multisystem processes drillAn 81-year-old woman with heart failure and atrial fibrillation who takes digoxin and furosemide is brought to the emergency department after 3 days of nausea, vomiting, and confusion; she reports seeing yellow halos around lights. Pulse is 44/min and blood pressure is 96/60 mm Hg. ECG shows atrial fibrillation with a slow ventricular response, frequent premature ventricular complexes, and runs of bidirectional ventricular tachycardia. Serum potassium is 6.1 mEq/L, creatinine is 2.4 mg/dL (1.1 mg/dL two months ago), and digoxin level is 4.2 ng/mL (therapeutic 0.5-2.0 ng/mL). Which of the following is the most appropriate pharmacotherapy?
Multisystem Processes & Disorders on Step 2 CK
Multisystem Processes & Disorders is 4–8% of Step 2 CK. It covers the patient who is sick everywhere at once: sepsis and shock, trauma, poisoning, environmental injury and infections that cross systems.
- Share of Step 2 CK
- 4–8% of the exam, per the USMLE content outline
- On our mock exam
- 19 of 316 questions, with your score for this system in the result
- Our drill
- 10 questions from 24 multisystem processes questions, untimed, a note on every option; one free attempt, unlimited with a pass
What Step 2 CK multisystem processes questions test
- Sepsis and septic shock: the first hour
- Trauma resuscitation: primary survey and its priorities
- Poisoning and overdose: antidotes and decontamination
- Heat stroke, hypothermia, drowning and bites
- Infections across systems and fever without a source
- Nutrition and perioperative assessment
Sit all 316 questions in timed blocks
316 questions in 16 timed 30-minute blocks, with your score in multisystem processes and every other content area.
Free multisystem processes drillHow to study it
- Learn the primary survey order and the first action at each step.
- Make a one-page antidote table.
- For sepsis, know the fluids, cultures and antibiotics sequence.
Common questions
Is toxicology on Step 2 CK?
Yes. Poisoning and overdose sit in Multisystem Processes & Disorders in our bank: recognizing the toxidrome and giving the right antidote.
How many questions on our mock?
19 of 316, inside the content outline’s 4–8% range.
316 questions in 16 timed 30-minute blocks, with your score in multisystem processes and every other content area.
Free multisystem processes drillThe other Step 2 CK systems
Sources
- USMLE: Step 1 (blocks, items, testing day, break time)
- USMLE: Step 2 CK (blocks, items, testing day, break time)
- USMLE: Test delivery software updates for Step 2 CK and Step 1 (May 2026)
- USMLE: Step 1 content outline and specifications
- USMLE: Step 2 CK content outline and specifications
- USMLE: Examination results and scoring (minimum passing scores)
- USMLE Bulletin: Scoring and score reporting (about 60% correct to pass; result timing)
- USMLE Bulletin: Eligibility (attempt limits)
- USMLE: Apply for exams (2026 and 2027 fees, FSMB registration, region fees)
- USMLE: Performance data (pass rates)
- Intealth ECFMG: Fees overview (ECFMG Certification)
Original practice questions written to the USMLE content outlines and current standard references. USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and NBME. Independent practice, not affiliated with or endorsed by the FSMB, NBME or Intealth (ECFMG). Follow current guidelines in clinical practice.