NCLEX-PN Safety and Infection Control Practice Questions
Safety and Infection Prevention and Control · 10–16% of the NCLEX-PN · Safe and Effective Care Environment
85 questions weighted to every client-needs category, three case studies, and a score for Safety and Infection Control so you know where you stand.
Free safety and infection control drillThe nurse on a postpartum unit brings a newborn from the nursery to a client's room for a feeding. Which action verifies that the newborn is being given to the correct parent?
Safety and Infection Prevention and Control on the 2026 PN test plan
Safety and Infection Prevention and Control is 10–16% of the NCLEX-PN. The 2026 test plan renamed it from Safety and Infection Control. Questions test the rules that protect clients and staff: precautions and PPE, client identification, falls, safe handling, restraints, allergies, security alerts and emergency response.
- Share of the exam
- 10–16% of scored stand-alone items (we weight our mock exams at 13%)
- Client Needs category
- Safe and Effective Care Environment
- Our drill
- 10 questions, untimed, a rationale for every option; one free attempt, unlimited with a pass
What Safety and Infection Control questions test
- Hand hygiene, standard, contact, droplet and airborne precautions and the conditions that need each; donning and doffing PPE in the right order
- Aseptic and sterile technique, sharps safety and soap and water for C. difficile
- Verifying client identity with two identifiers
- Safe client handling and transfer devices: gait belts, slide boards and mechanical lifts
- Fall, burn, poisoning and oxygen safety in facilities and in the home
- Least restrictive restraints and seclusion, alternatives and timed safety checks
- Allergies, including latex, and what to do when a reaction starts
- Security alerts (infant abduction, elopement), disaster response, fire response (RACE and PASS)
- Reporting practice errors and near misses with an incident report
Sit the full exam under the real clock
85 questions weighted to every client-needs category, three case studies, and a score for Safety and Infection Control so you know where you stand.
Free safety and infection control drillHow to study it
- Learn precautions by transmission route, not by disease list: airborne for tuberculosis, measles and varicella; droplet for influenza and pertussis; contact for C. difficile, MRSA and scabies.
- Safety questions usually have one option that removes the hazard right now; choose it over documenting, reporting or teaching.
- Restraints are a last resort with a time-limited order, regular checks and release; try the least restrictive alternative first.
- Take the drill twice and read the option notes: most misses here come from one half-remembered rule.
Common questions
Which conditions need airborne precautions?
Tuberculosis, measles, varicella (chickenpox) and disseminated herpes zoster. The client needs a negative-pressure room and staff wear a fitted N95 respirator. Droplet precautions (a surgical mask within close range) cover influenza, pertussis, mumps and meningococcal disease.
What does the fire response sequence RACE stand for?
Rescue anyone in immediate danger, Activate the alarm, Confine the fire by closing doors, and Extinguish or Evacuate. PASS describes the extinguisher: Pull, Aim at the base, Squeeze, Sweep.
What is the order for removing PPE?
Gloves first, then goggles or face shield, then gown, then mask or respirator, with hand hygiene right after removing everything (CDC sequence). Gown and gloves may come off together. The most contaminated items come off first, and the respirator is removed after leaving the room.
85 questions weighted to every client-needs category, three case studies, and a score for Safety and Infection Control so you know where you stand.
Free safety and infection control drillMore NCLEX-PN guides
- NCLEX-PN Coordinated Care Practice Questions
- NCLEX-PN Health Promotion Practice Questions
- NCLEX-PN Psychosocial Integrity Practice Questions
- NCLEX-PN Basic Care and Comfort Practice Questions
- NCLEX-PN Pharmacology Practice Questions
- NCLEX-PN Reduction of Risk Potential Practice Questions
- NCLEX-PN Physiological Adaptation Practice Questions
- NCLEX-PN Next Generation case studies
- NCLEX-PN vs NCLEX-RN
- Retaking the NCLEX-PN
- Studying for the NCLEX-RN instead? RN practice test
- NCLEX-PN practice exam (85 items)
Sources
- NCSBN: 2026 NCLEX-PN Test Plan (effective April 1, 2026)
- NCLEX.com: Test plans
- NCSBN: NCLEX Candidate Bulletin (October 2025): fees, retake policy, exam length and breaks
- NCSBN: NCLEX registration fee change effective February 1, 2027
- NCSBN: 2025 NCLEX Examination Statistics (NCLEX-PN volumes, pass rates and test length)
- NCLEX.com FAQs: partial-credit scoring (plus/minus, zero/one, rationale)
- NCSBN: Candidate Performance Report
Original practice questions for exam preparation, written to the 2026 NCLEX-PN Test Plan. Independent practice, not affiliated with or endorsed by the National Council of State Boards of Nursing (NCSBN) or Pearson VUE. NCLEX and NCLEX-PN are registered trademarks of NCSBN.