NAPLEX Patient Assessment and Treatment Planning Practice Questions

Domain 3 of the 2025 NAPLEX content outline, about 80 of the 200 scored questions (40%). The largest domain: medication and allergy histories, appropriateness of therapy, interactions, dosing errors, adverse reactions, toxicology, adherence, monitoring plans, patient education, OTC products and supplements, and devices.

225 questions in 6 hours across all five content domains, with an explanation for every answer and a score by domain.

Or try the free assessment and treatment planning drill
Free sample · Question 1 of 3Assessment and treatment planning

A patient with type 2 diabetes admits that she skips insulin doses near the end of each month because she cannot afford her copay. What is the pharmacist's most appropriate first action?

What Domain 3 covers

  • Medication history, allergy history and reconciliation
  • Health histories, screenings and assessments
  • Patient conditions and special populations: pathophysiology, appropriateness of therapy, interactions, errors and omissions, adverse drug reactions, toxicologic exposures and overdoses, adherence
  • Therapeutic monitoring and plan changes: goals, safety, effectiveness
  • Patient education: lifestyle, medication use and storage, disease management
  • Over-the-counter medications and dietary supplements
  • Devices and self-monitoring tests

Our full practice exam gives this domain 91 of its 225 questions, the outline’s share, and scores it separately.

Line drawing of a clipboard patient chart, a blood pressure cuff, a glucose meter and a weekly pill organizer
Free assessment and treatment planning drillTen questions with an explanation after each answer. The first attempt is free with a free account.

Then sit all 225 questions under the clock

225 questions in 6 hours across all five content domains, with an explanation for every answer and a score by domain.

Or try the free assessment and treatment planning drill

Common questions

How much of the NAPLEX is assessment and treatment planning?

Person-Centered Assessment and Treatment Planning is Domain 3 of the content outline effective May 1, 2025, 40% of the scored questions, about 80 of 200.

More NAPLEX guides

Source: NABP, NAPLEX Content Outline (effective May 1, 2025). Original independent practice; NAPLEX is a registered trademark of NABP. Not affiliated with or endorsed by NABP.