MPJE Controlled Substances Practice Questions
Controlled substances sit in Domain 3 of the MPJE and UMPJE outlines (inventory, record keeping, order forms, registration and power of attorney, theft and loss, disposal), and the prescription rules run through Domain 2. These federal rules apply everywhere; your state may be stricter.
120 questions in 2 hours 30 minutes across all four MPJE domains, with an explanation and citation for every answer.
Or try the free controlled substances law drillA physician who is not part of a narcotic treatment program writes a prescription for methadone tablets with the directions "for opioid use disorder maintenance." Under federal law, what should the pharmacist do?
Federal rules the exam tests
- A Schedule II prescription may not be refilled. 21 CFR 1306.12(a)
- After an emergency oral Schedule II prescription, the prescriber must deliver a written prescription for the emergency quantity within 7 days. 21 CFR 1306.11(d)(4)
- When a pharmacist cannot supply the full Schedule II quantity, the remainder may be filled within 72 hours; after that the prescriber is notified and no more is dispensed without a new prescription. 21 CFR 1306.13(a)
- Schedule III and IV prescriptions may be filled or refilled no more than 6 months after issue and refilled no more than 5 times. 21 CFR 1306.22(a)
- Labels of dispensed Schedule II, III and IV drugs carry the warning that federal law prohibits transfer of the drug to anyone other than the patient. 21 CFR 290.5
- A theft or significant loss is reported to the DEA Field Division in writing within one business day of discovery, and DEA Form 106 is filed within 45 days. 21 CFR 1301.76(b)
- A biennial inventory of all controlled substances on hand is taken at least every two years. 21 CFR 1304.11(c)
- A retail seller may not sell any purchaser more than 3.6 grams of pseudoephedrine base in a single calendar day. 21 CFR 1314.20(a)
Federal law sets the floor. Where a state rule is stricter, the state rule applies, and state MPJEs test it.
Free controlled substances law drillTen questions, each explained with the regulation or statute behind the answer. The first attempt is free with a free account.Then sit all 120 questions under the clock
120 questions in 2 hours 30 minutes across all four MPJE domains, with an explanation and citation for every answer.
Or try the free controlled substances law drillCommon questions
Which DEA form is used to order Schedule II drugs?
DEA Form 222, or its electronic equivalent through the Controlled Substance Ordering System (CSOS). Schedule III–V drugs are ordered on an invoice or other ordinary records.
Does federal law limit the days’ supply of a Schedule II prescription?
No. Federal law sets no quantity or days’-supply limit on a Schedule II prescription and no federal expiration date; many states do. Check your state’s rules.
More MPJE guides
Original independent practice; rules quoted from the current eCFR and U.S. Code. MPJE is a registered trademark of NABP. Not affiliated with or endorsed by NABP.